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GUIMARÃES,ZULMIRA A.S.; DAMATTA,RENATO A.; GUIMARÃES,RENAN S.; FILGUEIRA,MARCELLO. |
ABSTRACT With the aim of introducing permanent prostheses with main properties equivalent to cortical human bone, Ti-diamond composites were processed through powder metallurgy. Grade 1 titanium and mixtures of Ti powder with 2%, 5% and 10 wt% diamond were compacted at 100MPa, and then sintered at 1250°C/2hr/10-6mbar. Sintered samples were studied in the point of view of their microstructures, structures, yield strength and elastic modulus. The results showed that the best addition of diamonds was 2 wt%, which led to a uniform porosity, yield strength of 370MPa and elastic modulus of 13.9 GPa. Samples of Ti and Ti-2% diamond were subjected to in vitro cytotoxicity test, using cultures of VERO cells, and it resulted in a biocompatible and nontoxic composite... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biomaterials; Titanium; Diamond; Sintering; Characterization; Biocompatibility.. |
Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000603111 |
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Sun,S.X.; Guo,H.H.; Zhang,J.; Yu,B.; Sun,K.N.; Jin,Q.H.. |
A previous study showed that BMP-2 (bone morphogenetic protein-2) and wear debris can separately support osteoclast formation induced by the receptor activator of NF-κB ligand (RANKL). However, the effect of BMP-2 on wear debris-induced osteoclast formation is unclear. In this study, we show that neither titanium particles nor BMP-2 can induce osteoclast formation in RAW 264.7 mouse leukemic monocyte macrophage cells but that BMP-2 synergizes with titanium particles to enhance osteoclast formation in the presence of RANKL, and that at a low concentration, BMP-2 has an optimal effect to stimulate the size and number of multinuclear osteoclasts, expression of osteoclast genes, and resorption area. Our data also clarify that the effects caused by the increase... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bone morphogenetic protein; Titanium; Osteoclasts; SMAD; RANKL. |
Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000600461 |
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Laverne, Christine; Grauby, Olivier; Alt, Jeffrey C.; Bohn, Marcel. |
Hydroschorlomite, a Ti-, Ca-, Fe-rich andraditic garnet present in the deepest cores of basalts (661-749 mbsf) drilled in Hole 1256D during Ocean Drilling Program (ODP) Leg 206 (equatorial east Pacific), is reported here for the first time in oceanic crust. Detailed petrological and mineralogical studies by optical microscope, electron microprobe, scanning and transmission electron microscope, and micro-Raman spectroscopy are used to characterize this hydrogarnet and its relationships with other minerals. Hydroschorlomite occurs in Hole 1256D as small (5-50 mu m) anhedral or euhedral crystals associated either with celadonite in black halos adjacent to celadonite veins or with brown saponitic phyllosilicate in brown alteration halos adjacent to veins of... |
Tipo: Text |
Palavras-chave: Mineralogy and petrology : alteration and weathering processes; Mineralogy and petrology : hydrothermal systems; Hydrogarnet; Titanium; Alteration halo; Low temperature alteration; Oceanic basalt. |
Ano: 2006 |
URL: http://archimer.ifremer.fr/doc/2006/publication-2093.pdf |
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